Polyglutamic Acid is a natural biopolymer produced by Bacillus fermentation of soybeans. It is a superior humectant that can hold 4-5 times more water than hyaluronic acid. It forms a breathable moisture film on skin and inhibits hyaluronidase, the enzyme that breaks down natural HA.
Key Skin Benefits
+ Holds 4-5x more water than hyaluronic acid
+ Forms moisture-locking film on skin
+ Inhibits hyaluronidase (preserves natural HA)
+ Brightens skin by promoting NMF production
+ Natural, biodegradable, vegan
Pros
+ Superior to HA in water-binding capacity
+ Natural fermentation origin (natto beans)
+ HA-preservation effect is unique
+ Smooth, non-sticky feel
+ Excellent for dehydrated skin
Cons
− Less researched than HA
− High molecular weight limits penetration
− Film can feel tight if over-applied
− More expensive than glycerin or HA
− May interact with cationic ingredients
Specifications
Property
Value
Usage Areas
Face, Eye, Body, Hair
Product Type
Leave-On, Rinse-Off
Source
Biotech (fermentation)
Natural Level
Natural
Safety Ratings
Metric
Rating
Skin Sensitivity
0/5 (none)
Comedogenic Rating
0/5
EWG Score
1/10
Regional Regulatory Limits
Region
Leave-on %
Rinse-off %
Status
EU (CosIng)
No limit
No limit
Allowed
US (CIR/FDA)
No limit
No limit
Allowed
Japan (MHLW)
No limit
No limit
Allowed
ASEAN
No limit
No limit
Allowed
China (NMPA)
No limit
No limit
Allowed
Typical Usage % by Product Type
Product Type
Typical %
Hydrating serum
0.1 - 2%
Moisturizer
0.05 - 1%
Sheet mask
0.5 - 2%
References
Shih IL & Van YT (2001) — PGA production and applications. PMID: 11572941
Bajaj I & Singhal R (2011) — Polyglutamic acid review. PMID: 20004541